期刊
BIOSENSORS & BIOELECTRONICS
卷 52, 期 -, 页码 324-329出版社
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2013.09.005
关键词
Graphene oxide; Cerium oxide; Bioactive paper; Enzyme mimic; Lateral flow
类别
资金
- National Natural Science Foundation of China [21105126, 20820102037]
- 973 Project [2009CB930100, 2010CB933600]
- China Postdoctoral Science Foundation [2011M500126]
In this paper, Graphene oxide@SiO2@CeO2 hybrid nanosheets (GSCs) have been successfully synthesized by the wet-chemical strategy. TEM, FITR and XPS were applied to characterize the morphology and composition of the nanosheets. The colorimetric assay of these nanosheets indicated that they possessed high intrinsic peroxidase activity, which should be ascribed to the combination of graphene oxide and CeO2. A fully integrated reagentless bioactive paper based on GSCs was fabricated, which were able to simultaneously detect glucose, lactate, uric acid and cholesterol. The results demonstrated that GSCs have great potential as an alternative to the commonly employed peroxidase in daily nursing and general physical examination. (C) 2013 Elsevier B.V. All rights reserved.
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