期刊
BIOSENSORS & BIOELECTRONICS
卷 48, 期 -, 页码 270-275出版社
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2013.04.029
关键词
Cysteamine; NADH; Folic acid; NiO/CNTs nanocomposite
类别
资金
- Graduate University of Advanced Technology, Kerman, Iran
A carbon paste electrode (CPE) modified with (9, 10-dihydro-9, 10-ethanoanthracene-11, 12-dicarboximido)-4-ethylbenzene-1, 2-diol (DEDE) and NiO/CNTs nanocomposite was used for the sensitive voltammetric determination of cysteamine (CA), nicotinamide adenine dinucleotide (NADH) and folic acid (FA) for the first time. The synthesized materials were characterized with different methods such as XRD, cyclic voltammetry, electrochemical impedance spectroscopy (EIS) and square wave voltammetry (SWV). The modified electrode exhibited a potent and persistent electron mediating behavior followed by well-separated oxidation peaks of CA, NADH and FA. The peak currents were linearly dependent on CA, NADH and FA concentrations using square wave voltammetry (SWV) method in the ranges of 0.01-250, 1.0-500, and 3.0-550 mu mol L-1, with detection limits of 0.007, 0.6, and 0.9 mu mol L-1, respectively. The modified electrode was used for the determination of CA, NADH and FA in biological and pharmaceutical samples. (C) 2013 Elsevier B.V. All rights reserved.
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