期刊
BIOSENSORS & BIOELECTRONICS
卷 50, 期 -, 页码 331-337出版社
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2013.06.015
关键词
Reduced graphene oxide; Phenylboronic acid; Sugar sensing; Electrochemistry
类别
资金
- Centre National de Recherche Scientifique (CNRS)
- University Lille 1
- Nord Pas de Calais region
- Institut Universitaire de France (IUF)
- Natural Science Foundation of China [50972078]
- Chinese government for the China Scholarship Council
- European Regional Development Fund within Innovative Economy Operational Programme
A sensitive electrochemical active interface for sugar sensing based on the specific boronic acid-diol binding was established. The sensing matrix was formed by stirring a suspension of graphene oxide (GO) with 4-aminophenylboronic acid (APBA). The resulting composite consists of a water insoluble precipitate of reduced graphene oxide (rGO) with APBA incorporated into the rGO matrix. Differential pulse voltammetry (DPV) on glassy carbon electrodes modified with rGO/APBA was used for the detection of fructose, mannose and glucose. The fabricated sensor exhibited a wide linear range with detection limits of 100 nM for fructose, and around 800 nM for mannose and glucose. (C) 2013 Elsevier B.V. All rights reserved.
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