期刊
BIOSENSORS & BIOELECTRONICS
卷 50, 期 -, 页码 478-485出版社
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2013.07.014
关键词
Bilirubin oxidases; Bilirubin biosensors; Oxygen reduction; Biofuel cells; Mediated electron transfer; Direct electron transfer
类别
资金
- la Region Aquitaine
- Agence Nationale de la Recherche [ANR-12-BS08-0011-01]
- University of Bordeaux
- Agence Nationale de la Recherche (ANR) [ANR-12-BS08-0011] Funding Source: Agence Nationale de la Recherche (ANR)
Bilirubin oxidases, a sub class of the Multicopper oxidases family, were discovered in 1981 by Tanaka and Murao (Murao and Tanaka, 1981) and first used for the detection of bilirubin. Since 2001 and the pioneering work of Tsujimura, these BODs have attracted a lot of attention for the reduction of O-2. Unlike laccases, these BODs are stable in physiological conditions (20 mM phosphate buffer, pH 7.4, 0.14 M NaCl, 37 degrees C) and more than 120 papers have been published in the last 7 years. Here, we will first briefly describe some general features of BODs and then review the use of BODs for bilirubin biosensors and the recent achievements and progress toward the elaboration of efficient 02 reducing cathodes. (C) 2013 Elsevier B.V. All rights reserved.
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