期刊
NATURE PLANTS
卷 4, 期 3, 页码 148-151出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/s41477-018-0115-z
关键词
-
资金
- Institute for Basic Science [IBS-R021-D1]
Adenine base editors (ABEs), composed of an engineered deaminase and a catalytically impaired CRISPR-Cas9 variant, are powerful new tools for targeted base editing in cells and organisms. Together with cytosine base editors (CBEs), ABEs enable single-nucleotide conversions cleanly, efficiently and reversibly without double-stranded DNA cleavage, advancing genome editing in a new dimension.
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