A mimic peroxidase biosensor based on calcined layered double hydroxide for detection of H2O2

An enzymeless biosensor was explored from Cu-Mg-Al calcined layered double hydroxide (CLDH) modified electrode in this study. The Cu-Mg-Al CLDH greatly promotes the electron transfer between H2O2 and GCE, and it is exemplified toward the non-enzymatic sensing of H2O2. The results indicate that the Cu-Mg-Al CLDH exhibits excellent electrocatalytic property, high sensitivity, good reproducibility, long-term stability, and fast amperometric response toward reduction of H2O2, thus is promising for the future development of man-made mimics of enzyme in H2O2 sensors. This work opens a way to utilize simply Cu-Mg-Al CLDH as an electron mediator to fabricate an efficient H2O2 biosensor, which exhibits great potential applications in varieties of simple, robust, and easy-to-make analytical approaches in the future. (C) 2011 Elsevier B.V. All rights reserved.