Progress of Precision Nanomedicine-mediated Gas Therapy

The precision nanomedicine-mediated gas therapy as an emerging and promising therapy strategy has received increasing attention, due to its low toxicity and high efficacy. Recent studies show that the nanomedicine-mediated gas therapy can not only kill cancer cells in specific diseased sites, but also protect normal cells. This review summarizes and reviews the most recent progress of the nanomedicine-mediated gas therapy. We introduce the therapeutic effects and characteristics of the nanomedicine-mediated gas therapy firstly, and then review several main routes to realize the precision nanomedicine-mediated gas therapy, including targeted gas delivery, controlled gas release, biomedical imaging guidance-monitoring of gas therapy, multi-model combined therapy based on therapeutic gases, and so on, and finally summarize the present existing issues and the prospects of further development in the gas therapy field.