期刊
DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS
卷 12, 期 2, 页码 189-194出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.dsx.2017.09.007
关键词
Growth factors; Diabetic foot ulcer; Platelet rich plasma; Growth factors cocktail; Diabetes
Current advances in diabetic foot ulcers (DFU) treatment are discussed. Normal and pathological wound healing process are observed and the role of growth factors (GFs) is elucidated. Current techniques involving GFs and platelet rich plasma (PRP) are compared. Up-to-date research suggests that treatment with single growth factor (GF) could be insufficient and not encompassing all pathological changes in DFU bed. Efficiency of PRP is rather controversial and lacks evidence. Thus the use of cocktail of particular GFs is suggested. Pro et contra of each approach are discussed. (C) 2017 Published by Elsevier Ltd on behalf of Diabetes India.
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