期刊
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
卷 77, 期 10, 页码 2154-2156出版社
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.130454
关键词
transcription factor; Pou2f3; solitary chemosensory cell; differentiation; taste cell
类别
资金
- NIH [DC011143, DC00882, P30DC011735]
- Monell Institutional Fund
- [20570208]
Solitary chemosensory cells in the non-neuronal epithelium of the anterior nasal cavity have bitter taste cell-like molecular characteristics and are involved in the detection of noxious substances. Here, we demonstrate. that Pou2f3/Skn-1a, which is necessary for generation of sweet, umami, and bitter taste cells, is also necessary for the generation or differentiation of solitary chemosensory cells.
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