期刊
CHINESE JOURNAL OF CHEMISTRY
卷 36, 期 2, 页码 119-123出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cjoc.201700598
关键词
thiophenol; BODIPY; fluorescent probe; cell imaging
资金
- National Natural Science Foundation of China [21421005, 21422601, 21576037, U1608222]
Thiophenol has been listed as one of the main sources of pollution. Sensitive probes for thiophenol are very significant. Herein, a BODIPY-based fluorescent probe, named BDP, for poisonous thiophenol detection has been reported. BDP shows rapid response (15 s) and clear fluorescence enhancement (30 folds) to thiophenol in solution. The intensity of fluorescence and concentration of thiophenol have a good linear relationship. The detection limit is as low as 13.6 nmol L-1. BDP is stable towards pH and light radiation. Cell experiments demonstrate that BDP has good cell membrane penetrability, low cell toxicity and excellent imaging properties in living cells. Therefore, BDP has significant value on the detection of thiophenol in solution and in living cell.
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