期刊
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
卷 76, 期 7, 页码 1397-1400出版社
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.120076
关键词
Aurelia aurita; indomethacin; metamorphosis; screening; strobilation
类别
资金
- Graduate School of Biosphere Science of Hiroshima University
- Grants-in-Aid for Scientific Research [22580121] Funding Source: KAKEN
We found while screening a chemical library that indomethacin, an inhibitor of prostaglandin biosynthesis, induced strobilation (metamorphosis from the asexual to sexual stage) in the moon jellyfish, Aurelia aurita. Indomethacin initiated strobilation in a dose-dependent manner, but was not involved in the progression of strobilation. Pharmacological experiments suggested that indomethacin could induce strobilation independently of prostaglandin biosynthesis.
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