期刊
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
卷 76, 期 6, 页码 1229-1232出版社
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.110984
关键词
Pseudoalteromonas; prodigiosin; cytotoxicity; apoptosis
类别
资金
- Japan Science and Technology Agency [14-035]
Pseudoalteromonas sp. 1020R, isolated from the Pacific coast of Japan, produces prodigiosin family pigments. Structural analysis indicated that these are prodigiosin (2-methyl-3-pentyl-prodiginine) and three other prodigiosin congeners which differ only in the lengths of the alkyl side chains. These compounds exhibited different extents of cytotoxicity against U937 leukemia cells, and cell death was accompanied by typical features of apoptosis.
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