期刊
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
卷 76, 期 4, 页码 847-849出版社
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.110908
关键词
sinensetin; polymethoxyflavone; inflammation; inhibitor kappa B-alpha
类别
资金
- National Research Foundation of Korea (NRF) from the Ministry of Education, Science and Technology in Republic of Korea [2010-0007021]
- National Research Foundation of Korea [2010-0007021] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Sinensetin is one of the polymethoxyflavones (PMFs) having five methoxy groups on the basic benzo-gamma-pyrone skeleton with a carbonyl group at the C-4 position. We investigated in this study the anti-inflammatory activity of sinensetin in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. Sinensetin showed anti-inflammatory activity by regulating the protein level of inhibitor kappa B-alpha (I kappa B-alpha).
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