期刊
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
卷 75, 期 10, 页码 2079-2082出版社
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.110619
关键词
ganglioside; sialic acid; echinoderm; neurogenic activity
类别
资金
- MEXT of Japan [1701007, 22380067, 23688014]
- Grants-in-Aid for Scientific Research [22380067, 22658038, 21603007, 23688014] Funding Source: KAKEN
Synthesis of tetrasaccharide portion of ganglioside HPG-1 is described. The tetrasaccharide sequence, Fuc-alpha(1,8)-Neu5Gc-alpha(2,4)-Neu5Ac-alpha(2,6)-Glc, was successfully assembled by a linear strategy, in which the 1,5-lactamized sialyl galactose acceptor and the 8-O-Lev-N-Troc-sialic acid donor were exploited as key units.
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