New Steroidal Saponin from Hosta sieboldiana

An extract of the edible parts of Hosta sieboldiana suppressed the growth of P388 mouse leukemic cells. A new steroidal saponin was isolated from Hosta sieboldiana in this study, and the structure was determined by a spectroscopic analysis to be (25R)-3 beta-(alpha-L-rhamnopyranosyl-(1 -> 4)-beta-D-glucopyranosyl-(1 -> 3)-[beta-D-glucopyranosyl-(1 -> 2)]-beta-D-glucopyranosyl-(1 -> 4)-beta-D-galactopyranosyl)-5 alpha-spirostan-2 alpha-ol.