期刊
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
卷 74, 期 9, 页码 1960-1962出版社
OXFORD UNIV PRESS
DOI: 10.1271/bbb.100294
关键词
Laminaria angustata var. longissima; fucoidan; macrophage activation
We investigated macrophage activation by fucoidan from Laminaria angustata var. longissima in a murine macrophage cell line, RAW 264.7. The ratio of the chemical composition of the fucoidan was L-fucose: D-galactose:D-glucose:D-xylose:uronic acid:sulfate = 1.00:0.54:0.08:0.08:0.64:0.87. The fucoidan induced production of nitric oxide, tumor necrosis factor-alpha, and interleukin-6 in RAW 264.7 cells. These results indicate that the fucoidan induced macrophage activation.
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