期刊
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
卷 72, 期 7, 页码 1962-1964出版社
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.80118
关键词
Kothala-himbutu; thiocyclitol; alpha-glucosidase inhibitor; postprandial glucose level
A novel 13-membered ring thiocyclitol, isolated from an aqueous extract of Kothala-himbutu (Salacia reticulata), inhibited alpha-glucosidase in vitro. The inhibitory activity was investigated by maltose- and sucroseloading on Wistar rats. This study found significant lowering of postprandial glucose levels, and the potency of 13-membered ring thiocyclitol was confirmed in vivo.
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