期刊
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION
卷 103, 期 4, 页码 F388-F390出版社
BMJ PUBLISHING GROUP
DOI: 10.1136/archdischild-2017-313320
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资金
- National Institute for Health Research (NIHR) Biomedical Research Centre based at Imperial College Healthcare NHS Trust and Imperial College London
- Medical Research Council [MR/R001375/1, G1002276] Funding Source: researchfish
- National Institute for Health Research [NIHR/CS/010/022, ICA-CDRF-2016-02-071, HCS DRF-2014-05-013] Funding Source: researchfish
- MRC [MR/R001375/1, G1002276] Funding Source: UKRI
Although major cooling trials (and subsequent guidelines) excluded babies with mild encephalopathy, anecdotal evidence suggests that cooling is often offered to these infants. We report a national survey on current cooling practices for babies with mild encephalopathy in the UK. From 74 neonatal units contacted, 68 were cooling centres. We received 54 responses (79%) and included 48(five excluded due to incomplete data and one found later not to offer cooling). Of these, 36 centres(75%) offered cooling to infants with mild encephalopathy. Although most of the participating units reported targeting 33-34 degrees C core temperature, seven (19%) considered initiating cooling beyond 6 hours of age and 13 (36%) discontinued cooling prior to 72 hours. Babies were ventilated for cooling in two (6%) units and 13 (36%) sedated all cooled babies. Enteral feeding was withheld in 15 (42%) units and reduced below 25% of requirements in eight (22%) units. MRI and neurodevelopmental outcome evaluation were offered to all cooled babies in 29(80%) and 27(75%) units, respectively. Further research is necessary to ensure optimal neuroprotection in mild encephalopathy.
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