期刊
MOSCOW UNIVERSITY CHEMISTRY BULLETIN
卷 73, 期 5, 页码 244-247出版社
PLEIADES PUBLISHING INC
DOI: 10.3103/S0027131418050024
关键词
fraction of G(0)/G(1) diploid cells; chemotherapy efficacy; relapse-free survival; flow cytometry
The proportion of diploid cells in the G (0)/G (1) cell cycle phases was estimated by flow cytometry in 60 samples of stage III serous ovarian cancer tissue. The tumor tissue shows considerable heterogeneity with regard to the content of this tissue fraction, which ranged from 27 to 95% with a median of 73%. Statistically significant differences in the size of this fraction were identified by comparing tumor subgroups sensitive and resistant to first-line platinum-taxane chemotherapy. Predictive significance of the G (0)/G (1) fraction was concluded and quantitative evaluation of this fraction is recommended for clinical use.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据