期刊
BIORESOURCE TECHNOLOGY
卷 102, 期 18, 页码 8414-8422出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.biortech.2011.03.016
关键词
Metabolic engineering; Biohydrogen; Hydrogenase; Anaerobic metabolism
资金
- FQRNT (Le Fonds quebecois de la recherche sur la nature et les technologies)
- Ministry of Higher Education (Egypt)
Dark fermentation is an attractive option for hydrogen production since it could use already existing reactor technology and readily available substrates without requiring a direct input of solar energy. However, a number of improvements are required before the rates and yields of such a process approach those required for a practical process. Among the options for achieving the required advances, metabolic engineering offers some powerful tools for remodeling microbes to increase product production rates and molar yields. Here we review the current metabolic engineering tool box that is available, discuss the current status of engineering efforts as applied to dark hydrogen production, and suggest areas for future improvements. (C) 2011 Elsevier Ltd. All rights reserved.
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