期刊
BIORESOURCE TECHNOLOGY
卷 101, 期 22, 页码 8822-8827出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.biortech.2010.06.054
关键词
Bacillus amyloliquefaciens; Lipopeptide; Fengycin; Marine microorganisms
资金
- National High Technology Research and Development Program of China [2007AA09Z417]
- Chinese Academy of Sciences [KZCX2-YW-209]
- Network Laboratory for Coastal Zone Microbial Research, CAS [KSCX2-YW-G-073]
Bacillus amyloliquefaciens SH-B10 isolated from deep-sea sediment produces two anti-fungal lipopeptides that were purified by bioactivity-guided fractionation based on acid precipitation, vacuum flash chromatography and semi-preparative HPLC. The two compounds were identified by tandem Q-TOF mass spectroscopy as C16 fengycin A (1) and a new fengycin with an aminobutyric acid at position 6 of the peptide backbone (2). Both compounds showed significant inhibitory activities against five plant fungal pathogens in paper-agar disk diffusion assay. This is the first report on the anti-fungal activities of the rare 6-Abu fengycin lipopeptides, and at the same time provided an insight into the potential of marine microbial resource in biological control and sustainable agriculture. (C) 2010 Elsevier Ltd. All rights reserved.
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