期刊
THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY
卷 8, 期 2, 页码 73-92出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/2045125317743435
关键词
anorexia nervosa; bulimia; deep brain stimulation; eating disorders; non-invasive brain stimulation; obesity; transcranial direct current stimulation; transcranial magnetic stimulation
Eating disorders and obesity adversely affect individuals both medically and psychologically, leading to reduced life expectancy and poor quality of life. While there exist a number of treatments for anorexia, morbid obesity and bulimia, many patients do not respond favorably to current behavioral, medical or bariatric surgical management. Neuromodulation has been postulated as a potential treatment for eating disorders and obesity. In particular, deep brain stimulation and transcranial non-invasive brain stimulation have been studied for these indications across a variety of brain targets. Here, we review the neurobiology behind eating and eating disorders as well as the current status of preclinical and clinical neuromodulation trials for eating disorders and obesity.
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