Chiral resolution of phenylalanine by d-Phe imprinted membrane considering rejection property

An enantio-selective d-Phe imprinted P(AA-co-AN) membrane was prepared using the wet-phase inversion method. The membrane not only selectively adsorbed phenylalanine but also rejected it with a rejection selectivity of 0.82-0.64 and 0.91-0.63 during the filtration of 100 and 10 ppm (g m(-3)) racemate solutions, respectively. The fluxes of d-Phe and l-Phe during filtration of 10 ppm racemate solution were 0.0077-0.0229 and 0.0064-0.0208 mg m(-2) s(-1), respectively, and the fluxes of d-Phe and l-Phe during filtration of 100 ppm racemate solution were 0.1287-0.2522 and 0.1174-0.2458 mg m(-2) s(-1), respectively. The adsorption selectivity was higher at low concentration. The adsorption selectivities varied from 1.11 to 1.65 and from 1.64 to 2.78 during filtration of 100 and 10 ppm racemate solutions, respectively. In respect to desorption, the fractional difference between d-Phe and l-Phe in the recovered solution from 10 ppm was higher than that from 100 ppm.