期刊
BIOPOLYMERS
卷 94, 期 1, 页码 128-140出版社
WILEY
DOI: 10.1002/bip.21334
关键词
biomaterial; polysaccharide-modified polymer; polysaccharide conjugates; hydrogel
资金
- National Science Foundation [DGF-02-11651]
- National Institutes of Health [5-P20-RR015588, 1-ROI-EB003172]
- Arnold and Mabel Beckman Foundation
- Nemours Foundation
- NATIONAL CENTER FOR RESEARCH RESOURCES [P20RR015588] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB003172] Funding Source: NIH RePORTER
This review presents an overview of polysaccharide-conjugated synthetic polymers and their use in tissue-engineered scaffolds and drug-delivery applications. This topic will be divided into four categories: (1) polymeric materials modified with non-mammalian polysaccharides such as alginate, chitin, and dextran; (2) polymers modified with mammalian polysaccharides such as hyaluronan, chondroitin sulfate, and heparin; (3) multi-polysaccharide-derivatized polymer conjugate systems; and (4) polymers containing polysaccharidemimetic molecules. Each section will discuss relevant conjugation techniques, analysis, and the impact of these materials as micelles, particles, or hydrogels to sed in in-vitro and in-vivo biomaterial applications. (C) 2010 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 94: 128-140, 2010.
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