期刊
BIOPHYSICAL JOURNAL
卷 101, 期 6, 页码 L33-L35出版社
CELL PRESS
DOI: 10.1016/j.bpj.2011.08.023
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资金
- Japan Society for the Promotion of Science
- Ministry of Foreign and European Affairs
- Ministry of Education and Scientific Research
- Grants-in-Aid for Scientific Research [23740317] Funding Source: KAKEN
The magnitude of traction forces exerted by living animal cells on their environment is a monotonically increasing and approximately sigmoidal function of the stiffness of the external medium. We rationalize this observation using active matter theory, and propose that adaptation to substrate rigidity results from an interplay between passive elasticity and active contractility.
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