期刊
BIOPHYSICAL JOURNAL
卷 101, 期 4, 页码 970-975出版社
CELL PRESS
DOI: 10.1016/j.bpj.2011.06.060
关键词
-
类别
资金
- LLNL
- U.S. Department of Energy through the LLNL [DE-AC52-07NA27344]
Apolipoprotein A-I plays a central role in the solution structure of high-density lipoproteins. Determining the stoichiometry of lipid-bound apo A-I in the hydrated state is therefore fundamental to understanding how high-density lipoproteins form and function. Here, we use the quantum optical phenomenon of photon antibunching to determine the number of apo A-I molecules bound to discoidal lipoproteins and compare this with values obtained by photon-counting histogram analysis. Both the photon antibunching and photon-counting analyses show that reconstituted high-density lipoprotein particles contain two apo A-I molecules, which is in agreement with the commonly accepted double-belt model.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据