期刊
BIOPHYSICAL JOURNAL
卷 98, 期 3, 页码 412-417出版社
CELL PRESS
DOI: 10.1016/j.bpj.2009.10.036
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类别
资金
- National Science Foundation [EEC-0425626]
- Army Research Office [W911NF-08-1-0455]
- National Cancer Institute [R01 CA97391-01A1]
A platform of discrete microscopic magnetic elements patterned on a surface offers dynamic control over the motion of fluid-borne cells by reprogramming the magnetization within the magnetic bits. T-lymphocyte cells tethered to magnetic microspheres and untethered leukemia cells are remotely manipulated and guided along desired trajectories on a silicon surface by directed forces with average speeds up to 20 mu m/s. In addition to navigating cells, the microspheres can be operated from a distance to push biological and inert entities and act as local probes in fluidic environments.
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