3.8 Article

Comparison of tumor delineation using dual energy computed tomography versus magnetic resonance imaging in head and neck cancer re-irradiation cases

期刊

出版社

ELSEVIER
DOI: 10.1016/j.phro.2020.04.001

关键词

Re-irradiation; Head and neck; Dual energy computed tomography; Magnetic resonance imaging; Delineation

资金

  1. Australian Postgraduate Award
  2. RSNA Fellow Grant
  3. RANZCR research grants
  4. National Institutes of Health (NIH)
  5. National Institute for Dental and Craniofacial Research Establishing Outcome Measures Award [1R01DE025248/R56DE025248]
  6. Academic Industrial Partnership Grant [R01DE028290]
  7. National Science Foundation (NSF)
  8. Division of Mathematical Sciences
  9. Joint NIH/NSF Initiative on Quantitative Approaches to Biomedical Big Data (QuBBD) [NSF 1557679]
  10. National Institute of Biomedical Imaging and Bioengineering (NIBIB) Research Education Programs for Residents and Clinical Fellows Grant [R25EB025787-01]
  11. NIH Big Data to Knowledge (BD2K) Program of the National Cancer Institute (NCI) Early Stage Development of Technologies in Biomedical Computing, Informatics, and Big Data Science Award [1R01CA214825]
  12. NCI Early Phase Clinical Trials in Imaging and Image-Guided Interventions Program [1R01CA218148]
  13. NIH/NCI Cancer Center Support Grant (CCSG) Pilot Research Program Award from the UT MD Anderson CCSG Radiation Oncology and Cancer Imaging Program [P30CA016672]
  14. NIH/NCI Head and Neck Specialized Programs of Research Excellence (SPORE) Developmental Research Program Award [P50 CA097007]
  15. Elekta AB

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In treatment planning, multiple imaging modalities can be employed to improve the accuracy of tumor delineation but this can be costly. This study aimed to compare the interobserver consistency of using dual energy computed tomography (DECT) versus magnetic resonance imaging (MRI) for delineating tumors in the head and neck cancer (HNC) re-irradiation scenario. Twenty-three patients with recurrent HNC and had planning DECT and MRI were identified. Contoured tumor volumes by seven radiation oncologists were compared. Overall, T1c MRI performed the best with median DSC of 0.58 (0-0.91) for T1c. T1c MRI provided higher interobserver agreement for skull base sites and 60 kV DECT provided higher interobserver agreement for non-skull base sites.

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