Characterization, antibacterial, antioxidant, and cytotoxic activities of ZnO nanoparticles using Coptidis Rhizoma

Here, we report a simple, eco-friendly and inexpensive approach for the synthesis of zinc oxide nanopartides (ZnO NPs) using Coptidis Rhizome. The ZnO NPs were characterized by UV-visible absorption spectroscopy, FTIR, SEM-EDX, TGA, TEM, SAED and XRD. TEM images confirmed the presence of spherical and rod shaped ZnO NPs in the range of 2.90-25.20 nm. Green synthesized ZnO NPs exhibited moderate antibacterial activity against Gram-positive and Gram-negative bacteria and excellent DPPH free radical scavenging activity. Synthesized ZnO NPs had no toxic effects on the RAW 264.7 cell line. (C) 2014 Published by Elsevier Ltd.