期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 23, 期 7, 页码 1916-1922出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2013.02.017
关键词
Tacrine; Cholinesterase inhibitors; Multi-target-directed ligands; New tacrine hybrids; Hepatotoxicity; Alzheimer's disease
资金
- MICINN [SAF2006-08764-C02-01, SAF2009-07271, SAF2012-33304, SAF2010-20337]
- AECID (Ministerio de Asuntos Exteriores (Spain) [A1/035457/11]
- Tunisia
- UCM-Santander [GR35/10-B]
A summary of the recently published efforts on tacrine derivatives as a renewed potential therapeutic approach for the treatment of Alzheimer's disease is presented. (C) 2013 Elsevier Ltd. All rights reserved.
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