期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 22, 期 1, 页码 645-648出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2011.10.061
关键词
aza-Flavones; MicroRNA inhibitors; Drosophila; Cell cycle arrest; Apoptosis
资金
- RSC, UK
- CSIR, New Delhi [NWP-34]
aza-Flavanones have been identified as a new class of selective microRNA inhibitors. These compounds were found to arrest cell cycle via a novel cross species microRNA-dependent regulatory pathway interpreting an unexpected link between cell cycle arrest and microRNA mediated control in cancer. (C) 2011 Elsevier Ltd. All rights reserved.
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