期刊
NANOTECHNOLOGY AND PRECISION ENGINEERING-NAMI JISHU YU JINGMI GONGCHENG
卷 3, 期 3, 页码 126-140出版社
AIP Publishing
DOI: 10.1016/j.npe.2020.08.003
关键词
Sweat detection; Wearable biosensors; Electrochemical; Microfluidic chip; Capillary force; Evaporation pump
资金
- National Key Research and Development Program of China [2020YFC2004600, 2018YFE0205000]
- National Natural Science Foundation of China [81571766]
- Natural Science Foundation of Tianjin [17JCYBJC24400]
- 111 Project of China [B07014]
In recent years, analyses of sweat have become more popular since it doesn't require invasive sampling procedures. Although blood still remains the golden standards in clinical, analyses of other common body fluids, such as sweat, have become increasingly important. Because the compositions of sweat and blood are osmotically related, the content of certain metabolites in sweat can directly reflect the disease. Sweat detection can be used as an alternative to blood detection and allows continuous monitoring. Increased development of wearable sensors makes it possible for continuous sweat detection. Here, this paper gave a review about the sweat detection methods, such as fluorescence sensing, electrochemical sensing and colorimetric sensing. The advantages and disadvantages of each method and their developing trend in sweat detection were summarized. Then, for the problem of continuous sweat sampling, three methods (capillary force, hydrogel osmotic pump, evaporation-driven micropump) were introduced through different structures of microfluidic chip, and the level of sweat collection and transport achieved by related research was demonstrated. This review aims to provide guidance for future research in sweat detection and stimulate further interest in continuous monitoring of sweat using microfluidic chip. Copyright (C) 2020 Tianjin University. Publishing Service by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.
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