期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 20, 期 11, 页码 3413-3415出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2010.04.002
关键词
Dirhodium complex; Human colon adenocarcinoma cells
资金
- Fundacao para a Ciencia e Tecnologia
- FEDER [PTDC/QUI/66695/2006, POCI/QUI/58791/2004, SFRH/BD/17163/2004, SFRH/BD/40474/2007, BPD/46589/2008]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/17163/2004, SFRH/BD/40474/2007, PTDC/QUI/66695/2006, POCI/QUI/58791/2004] Funding Source: FCT
A novel dirhodium complex (Rh-2(L-PheAla)(2)(OAc)(2) is reported with strong activity towards human colon adenocarcinoma cells. Its effect was not accompanied by generation of reactive oxygen species (ROS) neither by activation of caspase-3. (C) 2010 Elsevier Ltd. All rights reserved.
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