4.5 Article

A selective 'Off-On' fluorescent sensor for Zn2+ based on hydrazone-pyrene derivative and its application for imaging of intracellular Zn2+

期刊

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 20, 期 1, 页码 125-128

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2009.11.028

关键词

Fluorescent chemosensor; Zinc sensor; Fluorescent probe; Pyrene

资金

  1. Ministry of Education, Science and Technology [20090083065, 20090063001]
  2. WCU [R32-2008-000-10180-0]

向作者/读者索取更多资源

A simple and effective fluorescent sensor based on hydrazone-pyrene has been synthesized. This probe displays a highly selective fluorescent enhancement with Zn2+, and application of this probe to detect the intrinsic Zn2+ ions present in pancreatic beta-cells was successfully demonstrated. (C) 2009 Elsevier Ltd. All rights reserved.

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