期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 19, 期 19, 页码 5569-5572出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2009.08.047
关键词
Click chemistry; Arthritis; Multicomponent; Michael reaction; Baylis Hillman
资金
- CSIR, New Delhi
- DST, New Delhi
Solvent free multicomponent reaction of Baylis Hillman acetate, TMS azide and arylnitrile to produce 1,5-disubstituted tetrazole is described. Some of these tetrazoles are found to be potential TNF-alpha inhibitors. (C) 2009 Elsevier Ltd. All rights reserved.
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