相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Exploiting the Microhomology-Mediated End-Joining Pathway in Cancer Therapy
Jeffrey Patterson-Fortin et al.
CANCER RESEARCH (2020)
Microhomology-mediated end joining: Good, bad and ugly
Ja-Hwan Seol et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2018)
DNA double-strand break response factors influence end-joining features of IgH class switch and general translocation junctions
Rohit A. Panchaksharia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Distinct roles of XPF-ERCC1 and Rad1-Rad10-Saw1 in replication-coupled and uncoupled inter-strand crosslink repair
Ja-Hwan Seol et al.
NATURE COMMUNICATIONS (2018)
Control of structure-specific endonucleases to maintain genome stability
Pierre-Marie Dehe et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
Non-homologous DNA end joining and alternative pathways to double-strand break repair
Howard H. Y. Chang et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
Mechanism and regulation of DNA end resection in eukaryotes
Lorraine S. Symington
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2016)
Detecting DNA double-stranded breaks in mammalian genomes by linear amplification-mediated high-throughput genome-wide translocation sequencing
Jiazhi Hu et al.
NATURE PROTOCOLS (2016)
Direct measurement of single-stranded DNA intermediates in mammalian cells by quantitative polymerase chain reaction
Yi Zhou et al.
ANALYTICAL BIOCHEMISTRY (2015)
Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching
Junchao Dong et al.
NATURE (2015)
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair
Raphael Ceccaldi et al.
NATURE (2015)
Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination
Pedro A. Mateos-Gomez et al.
NATURE (2015)
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
Tatiana Kent et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
DNA polymerases δ and λ cooperate in repairing double-strand breaks by microhomology-mediated end-joining in Saccharomyces cerevisiae
Damon Meyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Homology and enzymatic requirements of microhomology-dependent alternative end joining
S. Sharma et al.
CELL DEATH & DISEASE (2015)
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ
Tatiana Kent et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
PTIP associates with Artemis to dictate DNA repair pathway choice
Jiadong Wang et al.
GENES & DEVELOPMENT (2014)
Mouse SLX4 Is a Tumor Suppressor that Stimulates the Activity of the Nuclease XPF-ERCC1 in DNA Crosslink Repair
Michael R. G. Hodskinson et al.
MOLECULAR CELL (2014)
Substrate specificity of the MUS81-EME2 structure selective endonuclease
Alessandra Pepe et al.
NUCLEIC ACIDS RESEARCH (2014)
Quantitation of DNA double-strand break resection intermediates in human cells
Yi Zhou et al.
NUCLEIC ACIDS RESEARCH (2014)
Mechanisms of Programmed DNA Lesions and Genomic Instability in the Immune System
Frederick W. Alt et al.
CELL (2013)
RPA Accumulation during Class Switch Recombination Represents 5 '-3 ' DNA-End Resection during the S-G2/M Phase of the Cell Cycle
Arito Yamane et al.
CELL REPORTS (2013)
Promiscuous DNA synthesis by human DNA polymerase θ
Matthew Hogg et al.
NUCLEIC ACIDS RESEARCH (2012)
The TREX1 Exonuclease R114H Mutation in Aicardi-Goutieres Syndrome and Lupus Reveals Dimeric Structure Requirements for DNA Degradation Activity
Clinton D. Orebaugh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
The XPA-binding domain of ERCC1 Is Required for Nucleotide Excision Repair but Not Other DNA Repair Pathways
Barbara Orelli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4
Cristian Boboila et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination
Anne Bothmer et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
RAD5A, RECQ4A, and MUS81 Have Specific Functions in Homologous Recombination and Define Different Pathways of DNA Repair in Arabidopsis thaliana
Anja Mannuss et al.
PLANT CELL (2010)
Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70
Cristian Boboila et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Reduced immunoglobulin class switch recombination in the absence of Artemis
Paola Rivera-Munoz et al.
BLOOD (2009)
Coordination of Structure-Specific Nucleases by Human SLX4/BTBD12 Is Required for DNA Repair
Ivan M. Munoz et al.
MOLECULAR CELL (2009)
The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links
Ali Z. Al-Minawi et al.
NUCLEIC ACIDS RESEARCH (2009)
Structural and functional relationships of the XPF/MUS81 family of proteins
Alberto Ciccia et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2008)
Mechanism and regulation of class switch recombination
Janet Stavnezer et al.
ANNUAL REVIEW OF IMMUNOLOGY (2008)
The TREX1 Double-stranded DNA Degradation Activity Is Defective in Dominant Mutations Associated with Autoimmune Disease
Duane A. Lehtinen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination
Sonia Franco et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Altered kinetics of nonhomologous end joining and class switch recombination in ligase IV-deficient B cells
Li Han et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
ERCC1-XPF endonuclease facilitates DNA double-strand break repair
Anwaar Ahmad et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings
Mitch McVey et al.
TRENDS IN GENETICS (2008)
Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair
Nicole Bennardo et al.
PLOS GENETICS (2008)
The ERCC1/XPF endonuclease is required for efficient single-strand annealing and gene conversion in mammalian cells
Ali Z. Al-Minawi et al.
NUCLEIC ACIDS RESEARCH (2008)
Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease
Yun-Gui Yang et al.
CELL (2007)
Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA
Oleg V. Tsodikov et al.
EMBO JOURNAL (2007)
IgH class switching and translocations use a robust non-classical end-joining pathway
Catherine T. Yan et al.
NATURE (2007)
Saccharomyces cerevisiae Sae2- and tell-dependent single-strand DNA formation at DNA break promotes microhomology-mediated end joining
Kihoon Lee et al.
GENETICS (2007)
DNA-PKcs dependence of Artemis endonucleolytic activity, differences between hairpins and 5′ or 3′ overhangs
Doris Niewolik et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
DNA-PK autophosphorylation facilitates Artemis endonuclease activity
Aaron A. Goodarzi et al.
EMBO JOURNAL (2006)
Role of genomic instability and p53 in AID-induced c-myc-Igh translocations
AR Ramiro et al.
NATURE (2006)
Modulation of DNA end joining by nuclear proteins
L Liang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1
OV Tsodikov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells
Q Pan-Hammarström et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF
M Tian et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions
CE Schrader et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Gene-targeted mice lacking the Trex1 (DNase III) 3′→5′ DNA exonuclease develop inflammatory myocarditis
M Morita et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
msh2 separation of function mutations confer defects in the initiation steps of mismatch repair
AW Kijas et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
The repair and recombination enzyme ERCC1 is not required for immunoglobulin class switching
AG Winter et al.
DNA REPAIR (2003)
R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells
KF Yu et al.
NATURE IMMUNOLOGY (2003)
ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes
XD Zhu et al.
MOLECULAR CELL (2003)
Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences
JL Ma et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
DNA-dependent protein kinase activity is not required for immunoglobulin class switching
GC Bosma et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
The active site of the DNA repair endonuclease XPF-ERCC1 forms a highly conserved nuclease motif
JH Enzlin et al.
EMBO JOURNAL (2002)
IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells
JP Manis et al.
IMMUNITY (2002)
Transcription-induced cleavage of immunoglobulin switch regions by nucleotide excision repair nucleases in vitro
M Tian et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)