期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 18, 期 2, 页码 518-522出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2007.11.081
关键词
antibacterial; antifungal; flavonoids
Eleven flavonoid derivatives were synthesised using a modified Baker-Venkataraman rearrangement, and subsequent microwave-assisted closure of the heterocyclic ring. All of the synthetic compounds displayed antifungal activity against Aspergillus niger and Fusarium oxysporium, and two of the synthetic flavonoid analogues exhibited significant activity against methicillin-resistant Staphylococcus aureus. (c) 2007 Elsevier Ltd. All rights reserved.
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