4.5 Article

Microwave-assisted synthesis of dihydropyrimidin-2(1H)-ones using graphite supported lanthanum chloride as a mild and efficient catalyst

期刊

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 18, 期 1, 页码 278-280

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2007.10.087

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dihydropyrimidine; lanthanum chloride; Biginelli reaction; microwave

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Graphite supported lanthanum chloride efficiently catalyzes the three-component coupling of beta-ketoesters, aldehydes and urea/thiourea to afford corresponding dihydropyrimidinones in good yields under microwave irradiation. (C) 2007 Published by Elsevier Ltd.

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