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Cadherin-Bound β-Catenin Feeds into the Wnt Pathway upon Adherens Junctions Dissociation: Evidence for an Intersection between β-Catenin Pools
Yoonseok Kam et al.
PLOS ONE (2009)
LPA modulates monocyte migration directly and via LPA-stimulated endothelial cells
Cindy Gustin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)
Identification of the orphan GPCR, P2Y10 receptor as the sphingosine-1-phosphate and lysophosphatidic acid receptor
Masanori Murakami et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Lysophosphatidic acid and renal fibrosis
Jean-Philippe Pradere et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2008)
Two pathways for lysophosphatidic acid production
Junken Aoki et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2008)
Expression Patterns of the Lysophospholipid Receptor Genes During Mouse Early Development
Hideyo Ohuchi et al.
DEVELOPMENTAL DYNAMICS (2008)
Lysophosphatidic acid receptor-dependent secondary effects via astrocytes promote neuronal differentiation
Tania Cristina de Sampaio E. Spohr et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Lysophosphatidic Acid Receptors Determine Tumorigenicity and Aggressiveness of Ovarian Cancer Cells
Shuangxing Yu et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2008)
Role of LPA4/p2y9/GPR23 in Negative Regulation of Cell Motility
Zendra Lee et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Membrane lipids: where they are and how they behave
Gerrit van Meer et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Prevalence of chronic pain with neuropathic characteristics in the general population
Didier Bouhassira et al.
PAIN (2008)
Lysophosphatidic acid-induced interleukin-1β expression is mediated through Gi/Rho and the generation of reactive oxygen species in macrophages
Chi-Lun Chang et al.
JOURNAL OF BIOMEDICAL SCIENCE (2008)
Neuropathic pain - Redefinition and a grading system for clinical and research purposes
R. -D. Treede et al.
NEUROLOGY (2008)
Lipid peroxidation and antioxidant enzyme activities in vascular and Alzheimer dementias
Angela Casado et al.
NEUROCHEMICAL RESEARCH (2008)
Autotaxin: a secreted autocrine/paracrine factor that promotes glioma invasion
Dominique B. Hoelzinger et al.
JOURNAL OF NEURO-ONCOLOGY (2008)
The lysophosphatidic acid receptor LPA(1) links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak
Andrew M. Tager et al.
NATURE MEDICINE (2008)
Absence of LPA(1) signaling results in defective cortical development
Guillermo Estivill-Torrus et al.
CEREBRAL CORTEX (2008)
The orphan GPCR GPR87 was deorphanized and shown to be a lysophosphatidic acid receptor
Ken-Ichi Tabata et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
The lysophosphatidic acid type 2 receptor is required for protection
Wenlin Deng et al.
GASTROENTEROLOGY (2007)
LPA4/p2y9/GPR23 mediates rho-dependent morphological changes in a rat neuronal cell line
Keisuke Yanagida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
LPA4/GPR23 is a lysophosphatidic acid (LPA) receptor utilizing Gs-, Gq/Gi-mediated calcium signaling and G12/13-mediated Rho activation
Chang-Wook Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Lysophospholipid receptors: Signalling, pharmacology and regulation by lysophospholipid metabolism
Dagmar Meyer zu Heringdorf et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2007)
LPA-mediated demyelination in ex vivo culture of dorsal root
Ryousuke Fujita et al.
NEUROCHEMISTRY INTERNATIONAL (2007)
Lysophosphatidic acid stimulates neuronal differentiation of cortical neuroblasts through the LPA(1)-G(i/o) pathway
Nobuyuki Fukushima et al.
NEUROCHEMISTRY INTERNATIONAL (2007)
Astrocytogenesis of embryonic stem-cell-derived neural stem cells: default differentiation
Takashi Nakayama et al.
NEUROREPORT (2006)
Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid
Masayuki Tanaka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
GPR92 as a new G12/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5
Chang-Wook Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development
Laurens A. van Meeteren et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine TO lysophosphatidic acid
Yasuhiro Kishi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Actomyosin-dependent microtubule rearrangement in lysophosphatidic acid-induced neurite remodeling of young cortical neurons
Nobuyuki Fukushima et al.
BRAIN RESEARCH (2006)
Emerging medicinal roles for lysophospholipid signaling
SE Gardell et al.
TRENDS IN MOLECULAR MEDICINE (2006)
NPP-type ectophosphodiesterases: unity in diversity
C Stefan et al.
TRENDS IN BIOCHEMICAL SCIENCES (2005)
Gene expression profiles associated with response to chemotherapy in epithelial ovarian cancers
AA Jazaeri et al.
CLINICAL CANCER RESEARCH (2005)
LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing
XQ Ye et al.
NATURE (2005)
Rho kinase, a promising drug target for neurological disorders
BK Mueller et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
Neurochemical changes in LPA1 receptor deficient mice -: A putative model of schizophrenia
C Roberts et al.
NEUROCHEMICAL RESEARCH (2005)
Mechanisms of lysophosphatidic acid production
J Aoki
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2004)
Metabolic pathways and physiological and pathological significances of lysolipid phosphate mediators
A Tokumura
JOURNAL OF CELLULAR BIOCHEMISTRY (2004)
The ins and outs of lysophosphatidic acid signaling
WH Moolenaar et al.
BIOESSAYS (2004)
Genetics and cell biology of lysophosphatidic acid receptor-mediated signaling during cortical neurogenesis
MA Kingsbury et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2004)
Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells
D Shida et al.
EXPERIMENTAL CELL RESEARCH (2004)
Lysophospholipid receptors: Signaling and biology
I Ishii et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2004)
Vascular remodeling induced by naturally occurring unsaturated lysophosphatidic acid in vivo
K Yoshida et al.
CIRCULATION (2003)
Serum-derived factors weaken the barrier properties of cultured porcine brain capillary endothelial cells in vitro
T Nitz et al.
BRAIN RESEARCH (2003)
Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family
K Noguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Identification of an intracellular receptor for lysophosphatidic acid (LPA):: LPA is a transcellular PPARγ agonist
TM McIntyre et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding
MA Kingsbury et al.
NATURE NEUROSCIENCE (2003)
Inflammatory markers in matched plasma and cerebrospinal fluid from patients with Alzheimer's disease
YX Sun et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2003)
Pathogenesis of Parkinson's disease:: Dopamine, vesicles and α-synuclein
J Lotharius et al.
NATURE REVIEWS NEUROSCIENCE (2002)
Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase
A Tokumura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Characterization of lpa2 (Edg4) and lpa1/lpa2 (Edg2/Edg4) lysophosphatidic acid receptor knockout mice:: Signaling deficits without obvious phenotypic abnormality attributable to lpa2
JJA Contos et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases
BI Giasson et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Lysophosphatidic acid influences the morphology and motility of young, postmitotic cortical neurons
N Fukushima et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2002)
Interleukin-1 beta-induced substance P release from rat cultured primary afferent neurons driven by two phospholipase A2 enzymes: secretory type IIA and cytosolic type IV
N Morioka et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Regulation of Schwann cell morphology and adhesion by receptor-mediated lysophosphatidic acid signaling
JA Weiner et al.
JOURNAL OF NEUROSCIENCE (2001)
Phenotypic modulation of vascular smooth muscle cells induced by unsaturated lysophosphatidic acids
K Hayashi et al.
CIRCULATION RESEARCH (2001)
Direct quantitative analysis of lysophosphatidic acid molecular species by stable isotope dilution electrospray ionization liquid chromatography-mass spectrometry
DL Baker et al.
ANALYTICAL BIOCHEMISTRY (2001)
Lysophosphatidic acid synthesis and release
C Pagès et al.
PROSTAGLANDINS & OTHER LIPID MEDIATORS (2001)
Lysophospholipid receptors
N Fukushima et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2001)
Lysophosphatidic acid (LPA) is a novel extracellular regulator of cortical neuroblast morphology
N Fukushima et al.
DEVELOPMENTAL BIOLOGY (2000)
Requirement for the IpA1 lysophosphatidic acid receptor gene in normal suckling behavior
JJA Contos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species - Structure-activity relationship of cloned LPA receptors
K Bandoh et al.
FEBS LETTERS (2000)
Characterization of a novel sphingosine 1-phosphate receptor, Edg-8
DS Im et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
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