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Sandrine Faivre et al.
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Xiang Li et al.
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Rana R. McKay et al.
JOURNAL OF CLINICAL ONCOLOGY (2020)
FRACTION-RCC: Innovative, high-throughput assessment of nivolumab + ipilimumab for treatment-refractory advanced renal cell carcinoma (aRCC).
Toni K. Choueiri et al.
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Philippe Merle et al.
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Michael B. Atkins et al.
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Changhoon Yoo et al.
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Andrea S. Fung et al.
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Hyung-Don Kim et al.
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Alison L. Raybould et al.
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Toni Choueiri et al.
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Leonardo G. da Fonseca et al.
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Kohei Shigeta et al.
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Michael Teufel et al.
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Shixin Duan et al.
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Masatoshi Kudo
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Flavia Fondevila et al.
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Andrew X. Zhu et al.
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Sadahisa Ogasawara et al.
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Yuji Eso et al.
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Dal Fukurnura et al.
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G. K. Abou-Alfa et al.
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Anna Tutusaus et al.
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Gordon C. Jayson et al.
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Frank Erhard Uschner et al.
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Hand-foot skin reaction (HFSR) and overall survival (OS) in the phase 3 RESORCE trial of regorafenib for treatment of hepatocellular carcinoma (HCC) progressing on sorafenib.
Jordi Bruix et al.
JOURNAL OF CLINICAL ONCOLOGY (2018)
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Takuji Okusaka et al.
ESMO OPEN (2018)
Circulating angiogenesis-related markers as predictors of benefit from regorafenib in metastatic colorectal cancer (mCRC) patients (pts).
Carlotta Antoniotti et al.
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Incidence of Hepatocellular Carcinoma in All 50 United States, From 2000 Through 2012
Donna L. White et al.
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Survival by pattern of tumor progression during prior sorafenib (SOR) treatment in patients with hepatocellular carcinoma (HCC) in the phase III RESORCE trial comparing second-line treatment with regorafenib (REG) or placebo.
Jordi Bruix et al.
JOURNAL OF CLINICAL ONCOLOGY (2017)
Starting Dose of Sorafenib for the Treatment of Hepatocellular Carcinoma: A Retrospective, Multi-Institutional Study
Kim A. Reiss et al.
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Comparison of modified (m)RECIST and RECIST 1.1 assessments in the phase 3 RESORCE trial comparing regorafenib and placebo in patients with hepatocellular carcinoma who progressed during sorafenib treatment
J. Bruix et al.
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Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial
Jordi Bruix et al.
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Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial
Anthony B. El-Khoueiry et al.
LANCET (2017)
Non-transplant therapies for patients with hepatocellular carcinoma and Child-Pugh-Turcotte class B cirrhosis
Alessandro Granito et al.
LANCET ONCOLOGY (2017)
Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming
Lin Tian et al.
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A Multikinase and DNA-PK Inhibitor Combination Immunomodulates Melanomas, Suppresses Tumor Progression, and Enhances Immunotherapies
Alexander K. Tsai et al.
CANCER IMMUNOLOGY RESEARCH (2017)
Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy
Michael A. Cannarile et al.
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Radiologic criteria of response to systemic treatments for hepatocellular carcinoma
Francesco Tovoli et al.
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Tumor-associated macrophages in cancers
W. Hu et al.
CLINICAL & TRANSLATIONAL ONCOLOGY (2016)
Prognostic significance of adverse events in patients with hepatocellular carcinoma treated with sorafenib
Alessandro Granito et al.
THERAPEUTIC ADVANCES IN GASTROENTEROLOGY (2016)
Pharmacologic activity and pharmacokinetics of metabolites of regorafenib in preclinical models
Dieter Zopf et al.
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Bryony Simmons et al.
CLINICAL INFECTIOUS DISEASES (2015)
Assessment of Liver Function in Patients With Hepatocellular Carcinoma: A New Evidence-Based Approach-The ALBI Grade
Philip J. Johnson et al.
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Delivery of siRNA Using CXCR4-targeted Nanoparticles Modulates Tumor Microenvironment and Achieves a Potent Antitumor Response in Liver Cancer
Jia-Yu Liu et al.
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Hepatocellular carcinomas promote tumor-associated macrophage M2-polarization via increased B7-H3 expression
Fu-Biao Kang et al.
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Rakesh K. Jain
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Wei-Tien Tai et al.
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Roberta Schmieder et al.
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Jessica Dyson et al.
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Drug-drug interactions with tyrosine-kinase inhibitors: a clinical perspective
Roelof W. F. van Leeuwen et al.
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Regorafenib as second-line therapy for intermediate or advanced hepatocellular carcinoma: Multicentre, open-label, phase II safety study
Jordi Bruix et al.
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Lotfi Abou-Elkacem et al.
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D. Strumberg et al.
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Hashem B. El-Serag
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Valentina Santi et al.
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Gyoergy Baffy et al.
JOURNAL OF HEPATOLOGY (2012)
Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy
Yuhui Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Field-Practice Study of Sorafenib Therapy for Hepatocellular Carcinoma: A Prospective Multicenter Study in Italy
Massimo Iavarone et al.
HEPATOLOGY (2011)
Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity
Scott M. Wilhelm et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
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Ashwani K. Singal et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2010)
Outcome of Sustained Virological Responders With Histologically Advanced Chronic Hepatitis C
Timothy R. Morgan et al.
HEPATOLOGY (2010)
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Abby B. Siegel et al.
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Vascular normalization in Rgs5-deficient tumours promotes immune destruction
Juliana Hamzah et al.
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Sorafenib in advanced hepatocellular carcinoma
Josep M. Llovet et al.
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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
SM Wilhelm et al.
CANCER RESEARCH (2004)