Prevention of Anal Cancer

Article Medicine, General & Internal

Treatment of Anal High-Grade Squamous Intraepithelial Lesions to Prevent Anal Cancer

J. M. Palefsky et al.

Summary: Treatment for anal HSIL can significantly reduce the risk of anal cancer in persons living with HIV.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Article Immunology

The Natural History of Anal High-grade Squamous Intraepithelial Lesions in Gay and Bisexual Men

I. Mary Poynten et al.

Summary: This study found that factors such as younger age, HIV positivity, and persistent HPV16 infection were associated with a higher incidence of high-grade squamous intraepithelial lesions (HSIL). On the other hand, factors like younger age, smaller lesions, and absence of persistent HPV16 infection were associated with a higher clearance rate of HSIL.

CLINICAL INFECTIOUS DISEASES (2021)

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Article Oncology

DNA methylation markers have universal prognostic value for anal cancer risk in HIV-negative and HIV-positive individuals

Ramon P. van der Zee et al.

Summary: DNA methylation markers show high accuracy for detecting AIN3+ in both HIV-positive and HIV-negative risk groups, supporting the broad application of methylation analysis in anal cancer prevention programs.

MOLECULAR ONCOLOGY (2021)

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Review Medicine, General & Internal

Scanxiety: a scoping review about scan-associated anxiety

Kim Tam Bui et al.

Summary: The prevalence and severity of scanxiety varied widely in the studies due to heterogeneous measurement methods. A uniform approach to assessing scanxiety is needed to improve understanding of the phenomenon and guide interventions.

BMJ OPEN (2021)

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Article Immunology