Comparison between GenBody COVID-19 Rapid Antigen Kit and SARS-CoV-2 RT-PCR

Background: SARS-CoV-2 rapid antigen test can supplement the nucleic acid amplification method. Methods: We calculated the sensitivity and specificity of the GenBody COVID-19 antigen assay using 155 nasopharyngeal specimens. Results: The sensitivity in samples with their respective cycle thresholds varied from 33.3% to 100%; the sensitivity of the antigen assay was inferior to that of the gold standard polymerase chain reaction test. Conclusions: Considering the relatively fast speed of the antigen test and high sensitivity at a low cycle threshold value indicating a high viral load, the GenBody COVID-19 antigen test can be an easy and quick measure for detecting SARS-CoV-2 in individuals with high viral loads.

Automated summary

The study found that the sensitivity of the GenBody COVID-19 antigen assay is inferior to the polymerase chain reaction test, but its relatively fast speed and high sensitivity at low cycle threshold values indicating high viral loads make it a simple and quick measure for detecting SARS-CoV-2 in individuals with high viral loads.