期刊
BIOORGANIC & MEDICINAL CHEMISTRY
卷 16, 期 1, 页码 94-99出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmc.2007.04.056
关键词
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Detection of nucleic acid hybridization via fluorescence resonance energy transfer (FRET) using pyren-1-ylmethyl and perylen-3-ylmethyl NT-functionalized 2'-amino-LNA nucleosides incorporated into oligonucleotides exhibited a clear distance dependence of the FRET efficiency, ranging from below 10% when the fluorophores were approximately 40 A apart to approximately 90% when the fluorophores were in close proximity. (C) 2007 Elsevier Ltd. All rights reserved.
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