相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。C. elegans in high-throughput drug discovery
Linda P. O'Reilly et al.
ADVANCED DRUG DELIVERY REVIEWS (2014)
Activation of the NOTCH Pathway in Head and Neck Cancer
Wenyue Sun et al.
CANCER RESEARCH (2014)
Role of PUF-8/PUF Protein in Stem Cell Control, Sperm-Oocyte Decision and Cell Fate Reprogramming
Udaya Sree Datla et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2014)
Role of Oncogenic K-Ras in Cancer Stem Cell Activation by Aberrant Wnt/β-Catenin Signaling
Byoung-San Moon et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2014)
A high-content assay for identifying small molecules that reprogram C. elegans germ cell fate
Joshua A. Benson et al.
METHODS (2014)
The Notch Pathway Is Important in Maintaining the Cancer Stem Cell Population in Pancreatic Cancer
Ethan V. Abel et al.
PLOS ONE (2014)
A DTC Niche Plexus Surrounds the Germline Stem Cell Pool in Caenorhabditis elegans
Dana T. Byrd et al.
PLOS ONE (2014)
Discovery of two GLP-1/Notch target genes that account for the role of GLP-1/Notch signaling in stem cell maintenance
Aaron M. Kershner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
The Longevity Properties of 1,2,3,4,6-Penta-O-Galloyl-β-D-Glucose from Curcuma longa in Caenorhabditis elegans
Dalrae Ahn et al.
BIOMOLECULES & THERAPEUTICS (2013)
Wnt signaling in stem and cancer stem cells
Jane D. Holland et al.
CURRENT OPINION IN CELL BIOLOGY (2013)
PUF-8 negatively regulates RAS/MAPK signalling to promote differentiation of C. elegans germ cells
Samir Vaid et al.
DEVELOPMENT (2013)
DAF-2 and ERK Couple Nutrient Availability to Meiotic Progression during Caenorhabditis elegans Oogenesis
Andrew L. Lopez et al.
DEVELOPMENTAL CELL (2013)
Nicotine-motivated behavior in Caenorhabditis elegans requires the nicotinic acetylcholine receptor subunits acr-5 and acr-15
Laurie Sellings et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2013)
The structural basis of R-spondin recognition by LGR5 and RNF43
Po-Han Chen et al.
GENES & DEVELOPMENT (2013)
Structural basis for R-spondin recognition by LGR4/5/6 receptors
Dongli Wang et al.
GENES & DEVELOPMENT (2013)
Impacts of chronic low-level nicotine exposure on Caenorhabditis elegans reproduction: Identification of novel gene targets
Michael A. Smith et al.
REPRODUCTIVE TOXICOLOGY (2013)
Notch signaling in pancreatic cancer: oncogene or tumor suppressor?
Jacqueline L. Avila et al.
TRENDS IN MOLECULAR MEDICINE (2013)
The Ras-ERK MAPK regulatory network controls dedifferentiation in Caenorhabditis elegans germline
Dong Seok Cha et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)
Cancer Stem Cells: Current Status and Evolving Complexities
Jane E. Visvader et al.
CELL STEM CELL (2012)
Caenorhabditis elegans-based Model Systems for Antifungal Drug Discovery
Cleo G. Anastassopoulou et al.
CURRENT PHARMACEUTICAL DESIGN (2012)
Post-transcriptional regulation of the Ras-ERK/MAPK signaling pathway
Jarrett T. Whelan et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2012)
An In Vivo C. elegans Model System for Screening EGFR-Inhibiting Anti-Cancer Drugs
Young-Ki Bae et al.
PLOS ONE (2012)
被撤回的出版物: Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells (Retracted article. See vol. 423, pg. 153, 2018)
Bin Bao et al.
CANCER LETTERS (2011)
Role of Notch signaling in colon homeostasis and carcinogenesis
Shingo Miyamoto et al.
CANCER SCIENCE (2011)
C. elegans: An All in One Model for Antimicrobial Drug Discovery
B. Squiban et al.
CURRENT DRUG TARGETS (2011)
C. elegans: model host and tool for antimicrobial drug discovery
Jonathan J. Ewbank et al.
DISEASE MODELS & MECHANISMS (2011)
Notch signaling in lung cancer
Paola Galluzzo et al.
EXPERT REVIEW OF ANTICANCER THERAPY (2011)
STEM CELLS Orphan receptors find a home
Walter Birchmeier
NATURE (2011)
Notch signaling in glioblastoma: a developmental drug target?
Maria Maddalena Lino et al.
BMC MEDICINE (2010)
Targeting Notch signaling in pancreatic cancer
Elodie Ristorcelli et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2010)
Chemical reprogramming of Caenorhabditis elegans germ cell fate
Clinton T. Morgan et al.
NATURE CHEMICAL BIOLOGY (2010)
Wnt signaling in stem and cancer stem cells
Peter Wend et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2010)
MSP and GLP-1/Notch signaling coordinately regulate actomyosin-dependent cytoplasmic streaming and oocyte growth in C. elegans
Saravanapriah Nadarajan et al.
DEVELOPMENT (2009)
The Germinal Center Kinase GCK-1 Is a Negative Regulator of MAP Kinase Activation and Apoptosis in the C-elegans Germline
Katherine R. Schouest et al.
PLOS ONE (2009)
Target identification using drug affinity responsive target stability (DARTS)
Brett Lomenick et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Scratching the niche that controls Caenorhabditis elegans germline stem cells
Dana T. Byrd et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2009)
WNT signaling in stem cell biology and regenerative medicine
Masaru Katoh
CURRENT DRUG TARGETS (2008)
C-elegans La-related protein, LARP-1, localizes to germline P bodies and attenuates Ras-MAPK signaling during oogenesis
Keith Nykamp et al.
RNA (2008)
Multiple functions and dynamic activation of MPK-1 extracellular signal-regulated kinase signaling in Caenorhabditis elegans germline development
Min-Ho Lee et al.
GENETICS (2007)
Conserved regulation of MAP kinase expression by PUF RNA-binding proteins
Myon-Hee Lee et al.
PLOS GENETICS (2007)
Reciprocal asymmetry of SYS-1/β-catenin and POP-1/TCF controls asymmetric divisions in Caenorhabditis elegans
Bryan T. Phillips et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Controls of germline stem cells, entry into meiosis, and the Sperm/Oocyte decision in Caenorhabditis elegans
Judith Kimble et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY (2007)
A Critical Role for FBXW8 and MAPK in Cyclin D1 Degradation and Cancer Cell Proliferation
Hiroshi Okabe et al.
PLOS ONE (2006)
A C-elegans model of nicotline-dependent behavior:: Regulation by TRP-family channels
Zhaoyang Feng et al.
CELL (2006)
Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
Xing Fan et al.
CANCER RESEARCH (2006)
Wnt signaling and CEH-22/tinman/Nkx2.5 specify a stem cell niche in C-elegans
N Lam et al.
CURRENT BIOLOGY (2006)
LIP-1 phosphatase controls the extent of germline proliferation in Caenorhabditis elegans
MH Lee et al.
EMBO JOURNAL (2006)
Cyclin D regulation of a sexually dimorphic asymmetric cell division
C Tilmann et al.
DEVELOPMENTAL CELL (2005)
A β-catenin identified by functional rather than sequence criteria and its role in Wnt/MAPK signaling
AR Kidd et al.
CELL (2005)
Wnt signalling in stem cells and cancer
T Reya et al.
NATURE (2005)
FGF-20 and DKK1 are transcriptional targets of β-catenin and FGF-20 is implicated in cancer and development
MN Chamorro et al.
EMBO JOURNAL (2005)
Crosstalk between the EGFR and LIN-12/Notch pathways in C-elegans vulval development
AS Yoo et al.
SCIENCE (2004)
The phosphorylation status and anti-apoptotic activity of Bcl-2 are regulated by ERK and protein phosphatase 2A on the mitochondria
Y Tamura et al.
FEBS LETTERS (2004)
FBF-1 and FBF-2 regulate the size of the mitotic region in the C-elegans germline
LB Lamont et al.
DEVELOPMENTAL CELL (2004)
Involvement of mitogen-activated protein kinase in the cytokineregulated phosphorylation of transcription factor GATA-1
M Towatari et al.
HEMATOLOGY JOURNAL (2004)
The establishment of Caenorhabditis elegans germline pattern is controlled by overlapping proximal and distal somatic gonad signals
ASR Pepper et al.
DEVELOPMENTAL BIOLOGY (2003)
GLD-3, a Bicaudal-C homolog that inhibits FBF to control germline sex determination in C-elegans
CR Eckmann et al.
DEVELOPMENTAL CELL (2002)
The C.elegans MAPK phosphatase LIP-1 is required for the G2/M meiotic arrest of developing oocytes
A Hajnal et al.
EMBO JOURNAL (2002)
Notch inhibition of RAS signaling through MAP kinase phosphatase LIP-1 during C-elegans vulval development
T Berset et al.
SCIENCE (2001)
LAG-3 is a putative transcriptional activator in the C-elegans Notch pathway
AG Petcherski et al.
NATURE (2000)
分享论文
