4.7 Article

Pharmacokinetics and Safety of Bedaquiline in Human Immunodeficiency Virus-Positive and Negative Older Children and Adolescents With Rifampicin-Resistant Tuberculosis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Infectious Diseases

Treatment outcomes and safety in children with rifampicin-resistant TB

E. Lopez-Varela et al.

Summary: This study observed the outcomes and safety of rifampicin-resistant TB treatment in children. The results showed that the treatment outcomes were excellent in this cohort, with few severe adverse events related to treatment, except for hearing loss.

INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE (2022)

Article Immunology

Moxifloxacin Pharmacokinetics, Cardiac Safety, and Dosing for the Treatment of Rifampicin-Resistant Tuberculosis in Children

Kendra K. Radtke et al.

Summary: Limited data on the pharmacokinetics and safety of moxifloxacin in children, especially in those with rifampin-resistant tuberculosis, were evaluated in this study. The results suggest that higher doses of moxifloxacin are needed to achieve adult exposures in young children, and further safety assessment is required, particularly when coadministered with other QT-prolonging agents.

CLINICAL INFECTIOUS DISEASES (2022)

Article Infectious Diseases

Bedaquiline for multidrug-resistant TB in paediatric patients

R. Moodliar et al.

Summary: The TMC207-C211 study evaluated the pharmacokinetics and safety of bedaquiline in children with multidrug-resistant tuberculosis, showing comparable results to adults in terms of efficacy and safety after 24 weeks of treatment.

INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE (2021)

Article Infectious Diseases

Implementing novel regimens for drug-resistant TB in South Africa: what can the world learn?

N. Ndjeka et al.

INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE (2020)

Review Infectious Diseases

Re-Understanding the Mechanisms of Action of the Anti-Mycobacterial Drug Bedaquiline

Jickky Palmae Sarathy et al.

ANTIBIOTICS-BASEL (2019)

Article Pharmacology & Pharmacy

Relative bioavailability of bedaquiline tablets suspended in water: Implications for dosing in children

Elin M. Svensson et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2018)

Article Infectious Diseases

The burden of multidrug-resistant tuberculosis in children

H. E. Jenkins et al.

INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE (2018)

Article Microbiology

Population Pharmacokinetics of Bedaquiline (TMC207), a Novel Antituberculosis Drug

Sarah C. McLeay et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)

Review Infectious Diseases

Bedaquiline: a review of human pharmacokinetics and drug-drug interactions

R. P. G. van Heeswijk et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2014)

Article Medicine, General & Internal

Multidrug-Resistant Tuberculosis and Culture Conversion with Bedaquiline

Andreas H. Diacon et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Article Infectious Diseases

Consensus Statement on Research Definitions for Drug-Resistant Tuberculosis in Children

James A. Seddon et al.

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY (2013)

Article Pharmacology & Pharmacy

Prediction-Corrected Visual Predictive Checks for Diagnosing Nonlinear Mixed-Effects Models

Martin Bergstrand et al.

AAPS JOURNAL (2011)

Article Biochemistry & Molecular Biology

Diarylquinolines target subunit c of mycobacterial ATP synthase

Anil Koul et al.

NATURE CHEMICAL BIOLOGY (2007)

Article Computer Science, Interdisciplinary Applications

PsN-Toolkit - A collection of computer intensive statistical methods for non-linear mixed effect modeling using NONMEM

L Lindbom et al.

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE (2005)

Article Multidisciplinary Sciences

A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

K Andries et al.

SCIENCE (2005)