期刊
BIOCHEMICAL JOURNAL
卷 345, 期 -, 页码 181-184出版社
PORTLAND PRESS
DOI: 10.1042/0264-6021:3450181
关键词
ecto-enzyme; glycosylation; lysophosphatidate; phosphatidate phosphohydrolase
Lipid phosphate phosphatase-1 (LPP-1) dephosphorylates exogenous lysophosphatidate and thereby regulates the activation of lysophosphatidate receptors and cell division. Mutation of seven amino acids in three conserved domains of mouse LPP-1 abolished its activity. A glycosylation site was demonstrated between conserved Domains 1 and 2. LPP-1 is expressed in the plasma membrane, and the present results demonstrate the active site to be located on the outer surface.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据