期刊
BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK
卷 58, 期 6, 页码 493-507出版社
WALTER DE GRUYTER GMBH
DOI: 10.1515/bmt-2012-0058
关键词
iron oxide nanoparticles; magnetic particle imaging; magnetic relaxation
资金
- NIH [1R01EB013689-01/NIBIB, 1R41EB013520-01]
- NSF [IIP-1215556]
- UW/CGF
- Commercialization Fellowship (RMF)
Magnetic particle imaging (MPI) is an attractive new modality for imaging distributions of iron oxide nanoparticle tracers in vivo. With exceptional contrast, high sensitivity, and good spatial resolution, MPI shows promise for clinical imaging in angiography and oncology. Critically, MPI requires high-quality iron oxide nanoparticle tracers with tailored magnetic and surface properties to achieve its full potential. In this review, we discuss optimizing iron oxide nanoparticles' physical, magnetic, and pharmacokinetic properties for MPI, highlighting results from our recent work in which we demonstrated tailored, biocompatible iron oxide nanoparticle tracers that provided two times better linear spatial resolution and five times better signal-to-noise ratio than Resovist.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据