期刊
JOURNAL OF INFECTIOUS DISEASES
卷 181, 期 -, 页码 S244-S248出版社
UNIV CHICAGO PRESS
DOI: 10.1086/315570
关键词
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The massive diphtheria epidemic in the former Soviet Union provides important lessons for all diphtheria immunization programs: It is important to achieve a high Lever of childhood immunization, maintain immunity against diphtheria in older age groups, and use anti-epidemic measures, including immunization, to control epidemics in the early phase, The immunization coverage among children should be at least 90%. Further studies are needed to elaborate the most effective strategy to maintain immunity against diphtheria in adults (periodic booster doses, immunization of selected age groups in health care settings, use of Td [tetanus-diphtheria toxoids with reduced diphtheria toroid content] vaccine instead of monovalent tetanus toroid whenever tetanus toroid is indicated [e.g., in treatment of wounds or in school-based immunization programs]), Efforts should be undertaken to monitor diphtheria immunity in different groups by conducting age-specific serologic studies.
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