期刊
JOURNAL OF CELL SCIENCE
卷 128, 期 9, 页码 1661-1668出版社
COMPANY BIOLOGISTS LTD
DOI: 10.1242/jcs.168021
关键词
-
类别
资金
- National Science Foundation Graduate Research Fellowship
- Pew Scholars Program in the Biomedical Sciences
- National Institutes of Health [GM079320, GM100083]
Basement membranes are a dense, sheet-like form of extracellular matrix (ECM) that underlie epithelia and endothelia, and surround muscle, fat and Schwann cells. Basement membranes separate tissues and protect them from mechanical stress. Although traditionally thought of as a static support structure, a growing body of evidence suggests that dynamic basement membrane deposition and modification instructs coordinated cellular behaviors and acts mechanically to sculpt tissues. In this Commentary, we highlight recent studies that support the idea that far from being a passive matrix, basement membranes play formative roles in shaping tissues.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据