期刊
JOURNAL OF CLINICAL PERIODONTOLOGY
卷 27, 期 2, 页码 144-148出版社
MUNKSGAARD INT PUBL LTD
DOI: 10.1034/j.1600-051x.2000.027002144.x
关键词
gingival overgrowth; cyclosporin A; tacrolimus
Background: Unsightly gingival overgrowth affects many individuals immunosuppressed with cyclosporin A (CsA), Current management involves repeated periodontal surgery and intensive hygienist support. Tacrolimus is an effective alternative immunosuppressive agent for renal transplantation which does not appear to produce gingival enlargement. Aims: The purpose of the present study was to monitor the gingival response of 4 renal transplant patients (RTPs), with clinically significant CsA-induced,gingival overgrowth, after their immunosuppressive therapy was switched to tacrolimus. Methods: Intra-oral photographs and alginate impressions were taken both prior to the drug conversion and again, 6 to 9 months later. Gingival overgrowth scores were determined, from plaster models on both these occasions. Results: All of the RTPs experienced significant resolution of their gingival enlargement within the time period studied: however, only one had complete regression, Conclusion: It is concluded that conversion of RTPs with gingival overgrowth from CsA to tacrolimus may provide an effective management strategy for this clinical problem.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据